There tends to be a higher prevalence in older patients with alcoholism and debilitated hospitalized patients 3. 2000 Oct;63(10):721-8. The past 3 decades have seen the emergence of an invasive liver abscess syndrome caused by Klebsiella pneumoniae that may manifest with metastatic infection to the eye, brain, or lung [1, 2]. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases (in comparison, cavitation is rare in pneumococcal pneumonia). This occurs early and progresses quickly. Cavitary pulmonary disease. Klebsiella pneumonia is a necrotizing process with a predilection for debilitated people. 1 - 5 Although single case reports discuss the clinical presentation of pneumonia caused by Escherichia coli or Actinobacillus spp., 6, 7 to the authors’ knowledge no large retrospective studies describe the … Klebsiella pneumoniae is a bacterium that normally lives inside human intestines, where it doesn't cause disease.. {"url":"/signup-modal-props.json?lang=us\u0026email="}. Lobar expansion (e.g. Klebsiella pneumoniae is a Gram-negative, non-motile, encapsulated, lactose-fermenting, facultative anaerobic, rod-shaped bacterium.It appears as a mucoid lactose fermenter on MacConkey agar.. The Post-operative Abdomen - Surgicel … Pulmonary infection can also be classified into several radiologic and pathologic patterns according to its morphologic features. (2009) ISBN:0723434964. Unable to process the form. Br J Radiol. Chronic Klebsiella pneumonia: a rare manifestation of Klebsiella pneumonia. 87: 319. The organism Klebsiella pneumoniae was first described by German microbiologist Carl Friedländer (1847-1887) in 1882, in a series of patients with Klebsiella pneumonia 7,8. In comparison, cavitation is rare in pneumococcal pneumonia. Klebsiella pneumoniae (K. pneumoniae) are bacteria that normally live in your intestines and feces. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases. Klebsiella pneumoniae was first described by a German microbiologist and pathologist Carl Friedländer in 1882. [12,17] Aspiration pneumonia should always be suspected if the infiltrates are present bilaterally in the dependent or posterior portions of the lungs. 8. This organism can cause extensive pulmonary necrosis and frequent cavitation 1. ; Material is inoculated into blood agar and Mac Conkey agar medium and incubated aerobically. Klebsiella pneumonia usually results from aspiration of colonizing oropharyngeal microbes into the lower respiratory tract. Seventy of Klebsiella pneumoniae isolates had been collected from some Hospitals in Baghdad city from October to December 2017. It is not possible radiologically to pinpoint the causative organism. On CXR, consolidation is lobar and resembles streptococcus pneumonia. It has a high mortality rate of approximately 50% even with antimicrobial therapy. There can be variable features on chest HRCT which can also depend on current other organisms. 2008;21 (2): 305-33, table of contents. Figure Klebsiella pneumoniae liver abscess cases (n=123) in an outpatient parenteral antibiotic therapy (OPAT) cohort in Singapore, 2006–11 (n=2229) View Large Image Figure Viewer; Download Hi-res image Download (PPT) Roughly 70% of patients with K pneumoniae abscesses were men. 4. Klebsiella pneumoniae is among the most common Gram-negative bacteria encountered by physicians worldwide and accounts for 0.5-5.0% of all cases of pneumonia 2. Sputum analysis grew Klebsiella pneumoniae. Friedlander's pneumonia. In nosocomial pneumonia, patchy bronchial pneumonia is the most common finding and is likely caused by Gram-negative pathogens, especially Pseudomonas or Klebsiella. 5. Check for errors and try again. ADVERTISEMENT: Supporters see fewer/no ads. Mosby Incorporated. It is one of the causes that could be suspected when there is cavitatory pneumonia +/- a bulging fissure sign. Klebsiella species cause a wide range of diseases including pneumonia, urinary tract infections (UTIs), bloodstream infections and sepsis. (1968) Diseases of the chest. Klebsiella pneumoniae is a gram-negative, encapsulated, non-motile bacterium that is found in the environment and has been associated with pneumonia in the alcoholic and diabetic patient population. The disease is often overlooked in the Western physicians due to its rarity. the Western countries, Klebsiella pneumoniae invasive syn-drome (KPIS) should be alerted when patients present atypi-cal vague symptoms including fever, chill, nausea, vomiting, and right upper quadrant tenderness. The chest films of 58 patients with proved pneumonia due to Pseudomonas, Klebsiella, Enterobacter, Escherichia coli, Proteus, or Bacteroides were reviewed.Pseudomonas pneumonia was characterized by diffuse alveolar involvement with rapid progression to extensive macrocavitation. Moon WK, Im JG, Yeon KM et-al. All rights reserved. … Imaging of Diseases of the Chest. Continuous improvement of the lesion was found on follow-up chest X-rays. Klebsiella pneumoniae, a gram-negative organism, is an emerging common cause of PLA, particularly in patients with poorly controlled diabetes mellitus and without any pre-existing liver disease. K pneumoniae monomicrobial liver abscesses were associated with diabetes mellitus (P <.001), higher blood glucose levels at admission (P <.05), predominantly solid US appearances (P <.001), irregular or indistinct lesion margins (P <.05), less than 2 mL of pus aspirated (P <.001), and longer duration of antibiotic treatment (P <.05). These bacteria are harmless when they’re in … Volume: 242 Issue: 3 pp. Klebsiella pneumoniae(K. pneumoniae) is a Gram-negative, non-motile, capsulated, gas-producing enteric bacillus widely found in nature, and it belongs to the normal flora of the human oral cavity and intestine. The Brant and Helms Solution. Klebsiella pneumonia | Radiology Reference Article | Radiopaedia.org. by Wenlie Xie and Huixuan Jia. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases (in comparison, cavitation is rare in pneumococcal pneumonia). 3. Hoffman NR, Preston FS. There has been a considerable increase in the incidence of this type of pneumonia beginning in 1954 and reaching a peak in 1956, with 21 cases. ADVERTISEMENT: Supporters see fewer/no ads, Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Complications of Klebsiella pneumonia: CT evaluation. Clin. CT Appearance of Pyogenic Liver Abscesses Caused by Klebsiella pneumoniae. Acute Klebsiella pneumoniae pneumonia alone and with concurrent infection: comparison of clinical and thin-section CT findings. The bacterium typically colonizes human mucosal … 01 Jul 2011 Radiology. {"url":"/signup-modal-props.json?lang=us\u0026email="}. Microbiol. Hansell DM. Check for errors and try again. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. Case of the Week: August 27-September 3, 2009. Authors S ... diagnostic radiology studies, therapeutic modalities and risk factors associated with mortality were studied. Klebsiella is also responsible for a significant number of community-acquired infections. The hypervirulence of these novel community-acquired strains is mediated in part by their hypermucoviscous phenotypes associated with K1 and K2 capsule serotypes [ 3–5 ]. Chronic Klebsiella pneumonia was diagnosed and ceftazidime was changed to ceftriaxone 1 g every 12 h for 2 weeks. Imaging of Diseases of the Chest. See additional information. Conversely, various pathogens give rise to identical radiologic findings; e.g., bronchopneumonia can be caused by, for example, Staphylococcus aureus, Klebsiella, Proteus, or Pseudomonas. (2007) ISBN:B0011ZYZR2. Coronavirus: ... 2 Division of Diagnostic Radiology, Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand. VCU Department of Radiology VCU Medical Center. It is one of the causes that could be suspected when there is cavitatory pneumonia +/- a bulging fissure sign. Invasive community-acquired infections, including pyogenic liver abscesses, caused by hypervirulent Klebsiella pneumoniae (hvKp) strains have been well recognized worldwide. 2011;140 (4_MeetingAbstracts): . Ono A. Nineteen cases were seen in the first half of 1958. Among these, sporadic hvKp-related community-acquired pneumonia (CAP) is an acute-onset, rapidly progressing disease that can likely turn fatal, if left untreated. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). Rev. (2009) ISBN:0723434964. Klebsiella species are a Gram-negative rod shaped bacteria belonging to the Enterobacteriaceae family. Risk factors for Klebsiella pneumonia include alcoholism, diabetes mellitus, and COPD. There can b… Klebsiella pneumoniae renal abscess Zhonghua Yi Xue Za Zhi (Taipei). Klebsiella pneumoniae is a Gram-negative bacteria and a well-known cause of community-acquired pneumonia, which accounts for less than 5% of all cases of pneumonia. K. pneumoniaewas first discovered by Friedlander in 1882 and considered to be responsible for a severe form of lobar pneumonia. are commonly implicated as a cause of bacterial pneumonia in horses, but few reports describe the clinical presentation and progression of disease attributable to this organism. 1995;19 (2): 176-81. Klebsiella pneumoniae- Pathogenicity and Clinical Manifestations. The 70 isolates were taken from diverse clinical specimens. Path. Unable to process the form. Introduction . WebMD does not provide medical advice, diagnosis or treatment. 61-year-old woman with a long-standing history of alcohol abuse presented with a sudden onset of cough, pleuritic chest pain, dyspnea, fever, and rigors. 27-05-2014 - Klebsiella pneumonia is refers to a pneumonia resulting from an infection from the organism Klebsiella pneumoniae. This occurs early and progresses quickly. Volume: 260 Issue: 1 pp. Results: The mean age was 58.7 years and the male to female ratio was 10:14. Klebsiella spp. Radiology 2011. This occurs early and progresses quickly. Less common forms of infection include cellular bronchiolitis, septic embolism, miliary infection, and lung abscess. 53 (4): 481-6. Anat. Massive necrosis (pulmonary gangrene) is a recognized complication. E.Brant MW, A.Helms MC. On CXR, consolidation is lobar and resembles streptococcus pneumonia. J Comput Assist Tomogr. Klebsiella [kleb−see−ell−uh] is a type of Gram-negative bacteria that can cause different types of healthcare-associated infections, including pneumonia, bloodstream infections, wound or surgical site infections, and meningitis. K. pneumoniae is also a well-known cause of community-acquired pneumonia. Radiology 2007. To retrospectively compare the computed tomographic (CT) features of liver abscesses caused by Klebsiella pneumoniae with those caused by other bacterial pathogens. K. pneumoniae is found in the normal flora of skin, mouth and intestines, where it does not cause disease. After that, a 6-week course of amoxicillin-clavulanate (1 g every 12 h) was substituted. Hansell DM. 129-138. 1. Klebsiella pneumoniae is a Gram-negative bacillus with worldwide distribution that usually causes respiratory and urinary tract infections, ... Four weeks after admission, following discussion with Radiology, a thoracic CT scan was performed for subsequent biopsy of one of the pulmonary lesions. They are commonly found in the environment and in … It is an important type of pneumonia because of its severity, high incidence of complications, and elevated mortality [1]. However, in general, the type of microorganism implicated in pneumonia can be identified (bacteria, viruses, or fungi). Mosby Incorporated. Gadkowski LB, Stout JE. The three most common patterns are lobar pneumonia, bronchopneumonia, and interstitial pneumonia. In the setting of pneumonia, infection with K. pneumoniae is confirmed by either sputum culture analysis, blood culture analysis or midstream urine depending upon the illness. All K. pneumoniae isolates were identified based on API 20 E and Vitek2 compact system. 2010;83 (994): 854-60. 2. These infections are particularly a problem among neonates, elderly and immunocompromised individuals. bulging of the horizontal fissure in this case) is less common nowadays with modern antibiotic treatment. 769-776. Antibiotics sensitivity test was carried out toward 10 antibiotics using discs diffusion method. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. The presence of gram-negative rods in Gram-stained smears suggests Klebsiella; they maybe capsulated and non-sporing. Massive necrosis (pulmonary gangrene) is a recognized complication. Necrotizing pneumonia can occur as a complication 6. Often there can be extensive lobar opacification with air bronchograms. On CXR, consolidation is lobar and resembles streptococcus pneumonia. Okada F, Ando Y, Honda K et-al. Also, lobar expansion is not specific for Klebsiella infection. Often there can be extensive lobar opacification with air bronchograms. Lippincott Williams &Wilkins. (1882) Virchow Arch. Friedlander, C. Über die Pseudomyceten bei der acuten fibrinösen Pneumoniae. Diagnosis: Klebsiella pneumonia (aka Friedländer’s pneumonia) - Images, diagnosis, treatment options, review - Thoracic Imaging Case. The spectrum includes. Massive necrosis (pulmonary gangrene) is a recognized complication. A report of 11 cases and appraisal of antibiotic therapy. Pyogenic Liver Abscesses Caused by Klebsiella pneumoniae: US Appearance and Aspiration Findings. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). © 2005 - 2021 WebMD LLC. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). 6. Since 1950, 76 proved cases of pneumonia due to Staphylococcus aureus have been seen at the Los Angeles County Hospital. Klebsiella pneumonia, also known as Friedländer pneumonia, refers to pneumonia resulting from an infection from the organism Klebsiella pneumoniae. Extensive right upper lobe consolidation, with bulging of the horizontal fissure. CHEST Journal. Recommended Articles. 7.